Antibiotics weaken antiviral defense in the lung

Antibiotics may make the lung susceptible to flu viruses. This is a study on mice, conducted by scientists at the Francis Crick Institute in London showed. Reason could be taking a disturbed intestinal flora by the Antibiotic.

When mice with a normal intestinal flora were infected with the influenza virus survived for approximately 80 percent of them. If you did, however, get ahead of the infection is antibiotics survived only a third. This is due to a weakened bowel, could be flora. Antibiotics kill not only sick from the bacteria but also useful bacteria in the gut. The weakening, apparently, the defense in the lungs: The researchers found that signals from the intestinal bacteria contribute to a first line of defense against viruses in the lung mucosa to maintain.

"This is a further proof that antibiotics should not be taken off easily completed and dedicated. Improper use promotes antibiotic resistance and kills helpful intestinal bacteria, but can machen&quot also more susceptible to viruses;, study author Dr. Andreas Wack commented on the results of the research.

By intestinal bacteria get preparedness to maintain, prevents the rapid multiplication of the virus in the lung mucosa and valuable time gained. It takes about two days to immune cells to trigger a reaction. In this time the Virus multiplies in the lung mucosa. Two days after infection of antibiotic-treated mice had five times more viruses in the lungs. The immune system reacts to such a strong infection with a much greater response, which leads to more severe disease symptoms.