Symptoms are related to health-related quality of life (QoL) in patients with chronic kidney disease (CKD), according to a study published online June 23 in the Journal of Clinical Nursing.
Harith Eranga Yapa, Ph.D., from the School of Nursing at the Queensland University of Technology in Brisbane, Australia, and colleagues tested whether the revised Wilson and Cleary model could identify which factors contribute to health-related QoL in CKD. The analysis included 866 individuals with CKD who completed validated interviewer-administered questionnaires.
The researchers found that biological function (decreased kidney function and hemoglobin and greater number of comorbidities) directly contributed to increased symptom burden. There was a strong negative relationship observed between symptoms and both general health perceptions and health-related QoL, while general health perceptions had a direct positive relationship with health-related QoL. There were decreases in health-related QoL with increasing age. Half of the deterioration in health-related QoL was explained by the model.
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